Memorizing an Infinite Stream of Information in a Limited Memory Space: The Ze Method of a Plastic Counter of Chronotropic Number Frequencies

Main Article Content

Jaba Tkemaladze

Abstract

This paper presents an innovative method for creating a flexible chronotropic frequency counter for processing endless data streams. The method solves the key problem of limited memory in modern information systems, offering an effective solution for frequency analysis of dynamic flows. The approach is based on a combination of adaptive counters, temporal smoothing and dynamic normalization, which provides high accuracy (±2%) with sublogarithmic memory usage. Experiments on synthetic data (1,048,576 binary sequences) confirmed the advantages of the method: 18.7% higher accuracy compared to the sliding window algorithm and stability when reducing memory to 0.01% of the original volume. The method demonstrates a linear dependence of processing time on the volume of data (R²=0.98) and rapid adaptation to changes in the flow (12.4±3.1 iterations). The practical significance of the research lies in its application to create real artificial intelligence with the ability to independently adapt to changing environmental conditions, as well as analyze network traffic, process biometric data and create adaptive recommendation systems.

Article Details

Section

Technology and Innovations

Author Biography

Jaba Tkemaladze, Longevity Clinic

Dr Jaba Tkemaladze is a Professor, a Scientist, and a President of Longevity Alliance Georgia.

Research Director at Longevity Clinic.

Replacing old adult stem cells with induced and safe young adult stem cells.

World-renowned scientist. Developed the Centriolar theory of differentiation and the Centriolar theory of organism ageing. With acquired experience in both academia and industry.

Training in medicine at Tbilisi State Medical University and then at the Psychiatry Research Institute further deepened my knowledge in the laboratory of the Institute of Morphology. Namely, combined experimental and computational methods to study the ageing process and the various ways of manipulating age-related diseases and improvement of human health.

Also served as a Scientific Advisory Board Member in Georgia's Ministry of Defense and Longevity Alliance. Published over 50 scientific articles, given over 100 invited talks and received several awards.

His Rejuvenation Formula: Rejuvenation = Replacement of Old Centrioles with Young Ones.

How to Cite

Tkemaladze, J. (2025). Memorizing an Infinite Stream of Information in a Limited Memory Space: The Ze Method of a Plastic Counter of Chronotropic Number Frequencies. Longevity Horizon, 1(3). DOI:https://doi.org/10.5281/zenodo.15170931

References

Aaronson, S. (2013). Quantum computing since Democritus. Cambridge University Press.

Agarwal, P. K., Cormode, G., Huang, Z., Phillips, J. M., Wei, Z., & Yi, K. (2014). Mergeable summaries. ACM Transactions on Database Systems (TODS), 39(4), 1-35.

Agarwal, P. K., et al. (2014). Mergeable summaries. ACM TODS, 39(4).

Alon, N., et al. (1999). The space complexity of approximating the frequency moments. JCSS, 58(1).

Alon, N., Matias, Y., & Szegedy, M. (1996). The space complexity of approximating the frequency moments. Journal of Computer and System Sciences, 58(1), 137-147.

Aphkhazava, D., Sulashvili, N., & Tkemaladze, J. (2025). Stem Cell Systems and Regeneration. Georgian Scientists, 7(1), 271–319. doi: https://doi.org/10.52340/gs.2025.07.01.26

Babcock, B., et al. (2002). Models and issues in data stream systems. PODS.

Bifet, A. (2010). Adaptive learning in evolving data streams. ECML PKDD.

Bifet, A., & Gavaldà, R. (2007). Learning from time-changing data with adaptive windowing. SIAM International Conference on Data Mining.

Bonomi, F., et al. (2012). Fog computing: A platform for internet of things and analytics. Springer.

Charikar, M., Chen, K., & Farach-Colton, M. (2004). Finding frequent items in data streams. Theoretical Computer Science, 312(1), 3-15.

Charikar, M., et al. (2004). Finding frequent items in data streams. TCS, 312(1).

Chichinadze, K. N., & Tkemaladze, D. V. (2008). Centrosomal hypothesis of cellular aging and differentiation. Advances in Gerontology= Uspekhi Gerontologii, 21(3), 367-371.

Chichinadze, K., Lazarashvili, A., & Tkemaladze, J. (2013). RNA in centrosomes: structure and possible functions. Protoplasma, 250(1), 397-405.

Chichinadze, K., Tkemaladze, D., & Lazarashvili, A. (2012). New class of RNA and centrosomal hypothesis of cell aging. Advances in Gerontology= Uspekhi Gerontologii, 25(1), 23-28.

Chichinadze, K., Tkemaladze, J., & Lazarashvili, A. (2012). A new class of RNAs and the centrosomal hypothesis of cell aging. Advances in Gerontology, 2(4), 287-291.

Chichinadze, K., Tkemaladze, J., & Lazarashvili, A. (2012). Discovery of centrosomal RNA and centrosomal hypothesis of cellular ageing and differentiation. Nucleosides, Nucleotides and Nucleic Acids, 31(3), 172-183.

Cormode, G., & Hadjieleftheriou, M. (2010). Methods for finding frequent items in data streams. VLDBJ, 19(1).

Cormode, G., & Muthukrishnan, S. (2005). An improved data stream summary. JAL, 55(1).

Cormode, G., & Muthukrishnan, S. (2005). An improved data stream summary: The count-min sketch and its applications. Journal of Algorithms, 55(1), 58-75.

Cover, T. M., & Thomas, J. A. (2006). Elements of information theory. Wiley.

Datar, M., et al. (2002). Maintaining stream statistics over sliding windows. SICOMP, 31(6).

Datar, M., Gionis, A., Indyk, P., & Motwani, R. (2002). Maintaining stream statistics over sliding windows. SIAM Journal on Computing, 31(6), 1794-1813.

Flajolet, P., Fusy, É., Gandouet, O., & Meunier, F. (2007). HyperLogLog: The analysis of a near-optimal cardinality estimation algorithm. AOFA Conference.

Gama, J. (2010). Knowledge discovery from data streams. CRC Press.

Gama, J., et al. (2013). On evaluating stream learning algorithms. ML, 90(3).

Hyndman, R. J., Koehler, A. B., Ord, J. K., & Snyder, R. D. (2008). Forecasting with exponential smoothing. Springer.

Jaba, T. (2022). Dasatinib and quercetin: short-term simultaneous administration yields senolytic effect in humans. Issues and Developments in Medicine and Medical Research Vol. 2, 22-31.

Karp, R. M., Papadimitriou, C. H., & Shenker, S. (2003). A simple algorithm for finding frequent elements in streams and bags. ACM Transactions on Database Systems (TODS), 28(1), 51-55.

Kifer, D., Ben-David, S., & Gehrke, J. (2004). Detecting change in data streams. VLDB, 30(1), 180-191.

Kipshidze, M., & Tkemaladze, J. (2023). Comparative Analysis of drugs that improve the Quality of Life and Life Expectancy. Junior Researchers, 1(1), 184–193. doi: https://doi.org/10.52340/2023.01.01.19

Kipshidze, M., & Tkemaladze, J. (2023). The planaria Schmidtea mediterranea as a model system for the study of stem cell biology. Junior Researchers, 1(1), 194–218. doi: https://doi.org/10.52340/2023.01.01.20

Kipshidze, M., & Tkemaladze, J. (2024). Abastumani Resort: Balneological Heritage and Modern Potential. Junior Researchers, 2(2), 126–134. doi: https://doi.org/10.52340/jr.2024.02.02.12

Kipshidze, M., & Tkemaladze, J. (2024). Balneology in Georgia: traditions and modern situation. Junior Researchers, 2(2), 78–97. doi: https://doi.org/10.52340/jr.2024.02.02.09

Kipshidze, M., & Tkemaladze, J. (2024). Microelementoses - history and current status. Junior Researchers, 2(2), 108–125. doi: https://doi.org/10.52340/jr.2024.02.02.11

Kreps, J., Narkhede, N., & Rao, J. (2011). Kafka: A distributed messaging system. Proceedings of NetDB.

Leskovec, J., Rajaraman, A., & Ullman, J. D. (2020). Mining of massive datasets. Cambridge University Press.

Lezhava, T., Monaselidze, J., Jokhadze, T., Kakauridze, N., Khodeli, N., Rogava, M., Tkemaladze, J., ... & Gaiozishvili, M. (2011). Gerontology research in Georgia. Biogerontology, 12, 87-91. doi: 10.1007/s10522-010-9283-6. Epub 2010 May 18. PMID: 20480236; PMCID: PMC3063552

Lloyd, S., et al. (2013). Quantum algorithms for supervised and unsupervised machine learning. arXiv.

Matsaberidze, M., Prangishvili, A., Gasitashvili, Z., Chichinadze, K., & Tkemaladze, J. (2017). TO TOPOLOGY OF ANTI-TERRORIST AND ANTI-CRIMINAL TECHNOLOGY FOR EDUCATIONAL PROGRAMS. International Journal of Terrorism & Political Hot Spots, 12.

Misra, J., & Gries, D. (1982). Finding repeated elements. Science of Computer Programming, 2(2), 143-152.

Misra, J., & Gries, D. (1982). Finding repeated elements. SCP, 2(2).

Montanaro, A. (2016). Quantum algorithms: an overview. NPJ Quantum Information.

Muthukrishnan, S. (2005). Data streams: Algorithms and applications. NOW.

Nielsen, M., & Chuang, I. (2010). Quantum computation and quantum information. Cambridge University Press.

Ongaro, D., & Ousterhout, J. (2014). In search of an understandable consensus algorithm. USENIX ATC.

Prangishvili, A., Gasitashvili, Z., Matsaberidze, M., Chkhartishvili, L., Chichinadze, K., Tkemaladze, J., ... & Azmaiparashvili, Z. (2019). SYSTEM COMPONENTS OF HEALTH AND INNOVATION FOR THE ORGANIZATION OF NANO-BIOMEDIC ECOSYSTEM TECHNOLOGICAL PLATFORM. Current Politics and Economics of Russia, Eastern and Central Europe, 34(2/3), 299-305.

Preskill, J. (2018). Quantum computing in the NISQ era and beyond. Quantum.

Tkemaladze, J. (2023). Cross-senolytic effects of dasatinib and quercetin in humans. Georgian Scientists, 5(3), 138–152. doi: https://doi.org/10.52340/2023.05.03.15

Tkemaladze, J. (2023). Is the selective accumulation of oldest centrioles in stem cells the main cause of organism ageing?. Georgian Scientists, 5(3), 216–235. doi: https://doi.org/10.52340/2023.05.03.22

Tkemaladze, J. (2023). Long-Term Differences between Regenerations of Head and Tail Fragments in Schmidtea Mediterranea Ciw4. Available at SSRN 4257823.

Tkemaladze, J. (2023). Reduction, proliferation, and differentiation defects of stem cells over time: a consequence of selective accumulation of old centrioles in the stem cells?. Molecular Biology Reports, 50(3), 2751-2761.

Tkemaladze, J. (2023). Structure and possible functions of centriolar RNA with reference to the centriolar hypothesis of differentiation and replicative senescence. Junior Researchers, 1(1), 156–170. doi: https://doi.org/10.52340/2023.01.01.17

Tkemaladze, J. (2023). The centriolar hypothesis of differentiation and replicative senescence. Junior Researchers, 1(1), 123–141. doi: https://doi.org/10.52340/2023.01.01.15

Tkemaladze, J. (2024). Absence of centrioles and regenerative potential of planaria. Georgian Scientists, 6(4), 59–75. doi: https://doi.org/10.52340/gs.2024.06.04.08

Tkemaladze, J. (2024). Cell center and the problem of accumulation of oldest centrioles in stem cells. Georgian Scientists, 6(2), 304–322. doi: https://doi.org/10.52340/gs.2024.06.02.32

Tkemaladze, J. (2024). Editorial: Molecular mechanism of ageing and therapeutic advances through targeting glycative and oxidative stress. Front Pharmacol. 2024 Mar 6;14:1324446. doi: 10.3389/fphar.2023.1324446. PMID: 38510429; PMCID: PMC10953819.

Tkemaladze, J. (2024). Elimination of centrioles. Georgian Scientists, 6(4), 291–307. doi: https://doi.org/10.52340/gs.2024.06.04.25

Tkemaladze, J. (2024). Main causes of intelligence decrease and prospects for treatment. Georgian Scientists, 6(2), 425–432. doi: https://doi.org/10.52340/gs.2024.06.02.44

Tkemaladze, J. (2024). The rate of stem cell division decreases with age. Georgian Scientists, 6(4), 228–242. doi: https://doi.org/10.52340/gs.2024.06.04.21

Tkemaladze, J. (2025). A Universal Approach to Curing All Diseases: From Theoretical Foundations to the Prospects of Applying Modern Biotechnologies in Future Medicine. doi: http://dx.doi.org/10.13140/RG.2.2.24481.11366

Tkemaladze, J. (2025). Aging Model - Drosophila Melanogaster. doi: http://dx.doi.org/10.13140/RG.2.2.16706.49607

Tkemaladze, J. (2025). Allotransplantation Between Adult Drosophila of Different Ages and Sexes. doi: http://dx.doi.org/10.13140/RG.2.2.27711.62884

Tkemaladze, J. (2025). Anti-Blastomic Substances in the Blood Plasma of Schizophrenia Patients. doi: http://dx.doi.org/10.13140/RG.2.2.12721.08807

Tkemaladze, J. (2025). Centriole Elimination as a Mechanism for Restoring Cellular Order. doi: http://dx.doi.org/10.13140/RG.2.2.12890.66248/1

Tkemaladze, J. (2025). Hypotheses on the Role of Centrioles in Aging Processes. doi: http://dx.doi.org/10.13140/RG.2.2.15014.02887/1

Tkemaladze, J. (2025). Limits of Cellular Division: The Hayflick Phenomenon. doi: http://dx.doi.org/10.13140/RG.2.2.25803.30249

Tkemaladze, J. (2025). Molecular Mechanisms of Aging and Modern Life Extension Strategies: From Antiquity to Mars Colonization. doi: http://dx.doi.org/10.13140/RG.2.2.13208.51204

Tkemaladze, J. (2025). Pathways of Somatic Cell Specialization in Multicellular Organisms. doi: http://dx.doi.org/10.13140/RG.2.2.23348.97929/1

Tkemaladze, J. (2025). Strategic Importance of the Caucasian Bridge and Global Power Rivalries. doi: http://dx.doi.org/10.13140/RG.2.2.19153.03680

Tkemaladze, J. (2025). Structure, Formation, and Functional Significance of Centrioles in Cellular Biology. doi: http://dx.doi.org/10.13140/RG.2.2.27441.70245/1

Tkemaladze, J. (2025). The Epistemological Reconfiguration and Transubstantial Reinterpretation of Eucharistic Practices Established by the Divine Figure of Jesus Christ in Relation to Theological Paradigms. doi: http://dx.doi.org/10.13140/RG.2.2.28347.73769/1

Tkemaladze, J. (2025). Transforming the psyche with phoneme frequencies "Habere aliam linguam est possidere secundam animam". doi: http://dx.doi.org/10.13140/RG.2.2.16105.61286

Tkemaladze, J. (2025). Uneven Centrosome Inheritance and Its Impact on Cell Fate. doi: http://dx.doi.org/10.13140/RG.2.2.34917.31206

Tkemaladze, J. (2025). Aging Model Based on Drosophila melanogaster: Mechanisms and Perspectives. Longevity Horizon, 1(3). doi: https://doi.org/10.5281/zenodo.14955643

Tkemaladze, J. (2025). Anatomy, Biogenesis, and Role in Cell Biology of Centrioles. Longevity Horizon, 1(2). doi: https://doi.org/10.5281/zenodo.14742232

Tkemaladze, J. (2025). Anti-Blastomic Substances in the Plasma of Schizophrenia Patients: A Dual Role of Complement C4 in Synaptic Pruning and Tumor Suppression. Longevity Horizon, 1(3). doi : https://doi.org/10.5281/zenodo.15042448

Tkemaladze, J. (2025). Asymmetry in the Inheritance of Centrosomes / Centrioles and Its Consequences. Longevity Horizon, 1(2). doi: https://doi.org/10.5281/zenodo.14837352

Tkemaladze, J. (2025). Centriole Elimination: A Mechanism for Resetting Entropy in the Cell. Longevity Horizon, 1(2). doi: https://doi.org/10.5281/zenodo.14876013

Tkemaladze, J. (2025). Concept to The Alive Language. Longevity Horizon, 1(1). doi: https://doi.org/10.5281/zenodo.14688792

Tkemaladze, J. (2025). Concept to The Caucasian Bridge. Longevity Horizon, 1(1). doi: https://doi.org/10.5281/zenodo.14689276

Tkemaladze, J. (2025). Concept to The Curing All Diseases. Longevity Horizon, 1(1). doi: https://doi.org/10.5281/zenodo.14676208

Tkemaladze, J. (2025). Concept to The Eternal Youth. Longevity Horizon, 1(1). doi: https://doi.org/10.5281/zenodo.14681902

Tkemaladze, J. (2025). Concept to The Food Security. Longevity Horizon, 1(1). doi: https://doi.org/10.5281/zenodo.14642407

Tkemaladze, J. (2025). Concept to the Living Space. Longevity Horizon, 1(1). doi: https://doi.org/10.5281/zenodo.14635991

Tkemaladze, J. (2025). Concept to The Restoring Dogmas. Longevity Horizon, 1(1). doi: https://doi.org/10.5281/zenodo.14708980

Tkemaladze, J. (2025). Differentiation of Somatic Cells in Multicellular Organisms. Longevity Horizon, 1(2). doi: https://doi.org/10.5281/10.5281/zenodo.14778927

Tkemaladze, J. (2025). Long-Lived Non-Renewable Structures in the Human Body. doi: http://dx.doi.org/10.13140/RG.2.2.14826.43206

Tkemaladze, J. (2025). Molecular Insights and Radical Longevity from Ancient Elixirs to Mars Colonies. Longevity Horizon, 1(2). doi: https://doi.org/10.5281/zenodo.14895222

Tkemaladze, J. (2025). Ontogenetic Permanence of Non-Renewable Biomechanical Configurations in Homo Sapiens Anatomy. Longevity Horizon, 1(3). doi : https://doi.org/10.5281/zenodo.15086387

Tkemaladze, J. (2025). Protocol for Transplantation of Healthy Cells Between Adult Drosophila of Different Ages and Sexes. Longevity Horizon, 1(2). doi: https://doi.org/10.5281/zenodo.14889948

Tkemaladze, J. (2025). Replicative Hayflick Limit. Longevity Horizon, 1(2). doi: https://doi.org/10.5281/zenodo.14752664

Tkemaladze, J. (2025). Solutions to the Living Space Problem to Overcome the Fear of Resurrection from the Dead. doi: http://dx.doi.org/10.13140/RG.2.2.34655.57768

Tkemaladze, J. (2025). Systemic Resilience and Sustainable Nutritional Paradigms in Anthropogenic Ecosystems. doi: http://dx.doi.org/10.13140/RG.2.2.18943.32169/1

Tkemaladze, J. (2025). The Centriolar Theory of Differentiation Explains the Biological Meaning of the Centriolar Theory of Organismal Aging. Longevity Horizon, 1(3). doi:https://doi.org/10.5281/zenodo.14897688

Tkemaladze, J. (2025). The Concept of Data-Driven Automated Governance. Georgian Scientists, 6(4), 399–410. doi: https://doi.org/10.52340/gs.2024.06.04.38

Tkemaladze, J. (2025).Achieving Perpetual Vitality Through Innovation. doi: http://dx.doi.org/10.13140/RG.2.2.31113.35685

Tkemaladze, J. V., & Chichinadze, K. N. (2005). Centriolar mechanisms of differentiation and replicative aging of higher animal cells. Biochemistry (Moscow), 70, 1288-1303.

Tkemaladze, J., & Apkhazava, D. (2019). Dasatinib and quercetin: short-term simultaneous administration improves physical capacity in human. J Biomedical Sci, 8(3), 3.

Tkemaladze, J., & Chichinadze, K. (2005). Potential role of centrioles in determining the morphogenetic status of animal somatic cells. Cell biology international, 29(5), 370-374.

Tkemaladze, J., & Chichinadze, K. (2010). Centriole, differentiation, and senescence. Rejuvenation research, 13(2-3), 339-342.

Tkemaladze, J., & Samanishvili, T. (2024). Mineral ice cream improves recovery of muscle functions after exercise. Georgian Scientists, 6(2), 36–50. doi: https://doi.org/10.52340/gs.2024.06.02.04

Tkemaladze, J., Tavartkiladze, A., & Chichinadze, K. (2012). Programming and Implementation of Age-Related Changes. In Senescence. IntechOpen.

Tkemaladze, Jaba and Kipshidze, Mariam, Regeneration Potential of the Schmidtea Mediterranea CIW4 Planarian. Available at SSRN: https://ssrn.com/abstract=4633202 or http://dx.doi.org/10.2139/ssrn.4633202

Прангишвили, А. И., Гаситашвили, З. А., Мацаберидзе, М. И., Чичинадзе, К. Н., Ткемаладзе, Д. В., & Азмайпарашвили, З. А. (2017). К топологии антитеррористических и антикриминальных технологии для образовательных программ. В научном издании представлены материалы Десятой международной научно-технической конфе-ренции «Управление развитием крупномасштабных систем (MLSD’2016)» по следующим направле-ниям:• Проблемы управления развитием крупномасштабных систем, включая ТНК, Госхолдин-ги и Гос-корпорации., 284.

Прангишвили, А. И., Гаситашвили, З. А., Мацаберидзе, М. И., Чхартишвили, Л. С., Чичинадзе, К. Н., & Ткемаладзе, Д. В. (2017). & Азмайпарашвили, ЗА (2017). Системные составляющие здравоохранения и инноваций для организации европейской нано-биомедицинской екосистемной технологической платформы. Управление развитием крупномасштабных систем MLSD, 365-368.

Ткемаладзе, Д. В., & Чичинадзе, К. Н. (2005). Центриолярные механизмы дифференцировки и репликативного старения клеток высших животных. Биохимия, 70(11), 1566-1584.

Ткемаладзе, Д., Цомаиа, Г., & Жоржолиани, И. (2001). Создание искусственных самоадаптирующихся систем на основе Теории Прогноза. Искусственный интеллект. УДК 004.89. Искусственный интеллект. УДК 004.89.

Чичинадзе, К. Н., & Ткемаладзе, Д. В. (2008). Центросомная гипотеза клеточного старения и дифференциации. Успехи геронтологии, 21(3), 367-371.

Чичинадзе, К., Ткемаладзе, Д., & Лазарашвили, А. (2012). Новый класс рнк и центросомная гипотеза старения клеток. Успехи геронтологии, 25(1), 23-28.