Theory of Lifespan Decline

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Published: 2025-09-17
DOI: https://doi.org/10.5281/zenodo.17142909
Keywords:
Lifespan Decline, Biogerontology, Life-History Theory, Genetic Bottleneck, Postdiluvian Adaptation, Biblical Longevity, Somatic Maintenance, Reproductive Trade-Off, Divine Action

Main Article Content

Jaba Tkemaladze
Longevity Clinic
https://orcid.org/0000-0001-8651-7243

Abstract

The dramatic decline in human lifespan described in the biblical genealogies of Genesis 5 and 11 presents a unique intersection of theological narrative and biological inquiry. This paper proposes a multidisciplinary theory to explain this phenomenon, integrating textual analysis with principles from biogerontology and population genetics. We argue that the Genesis Flood narrative represents a catastrophic event that triggered a fundamental shift in human life-history strategy. Statistical analysis of the biblical data reveals a synchronized decline in total lifespan, age at sexual maturity, and reproductive window—a triad consistent with an adaptive transition from a slow to a fast life-history strategy in response to postdiluvian environmental harshness and a genetic bottleneck. This model explains the decline as a trade-off favoring rapid reproduction over somatic maintenance. The case of Job’s divinely granted 140 years is analyzed not as a reversion to antediluvian norms, but as a supernatural blessing within the new biological paradigm, affirming divine sovereignty over natural law. The study concludes that the biblical account, while theological in purpose, exhibits an internal consistency with modern biological principles, offering a coherent framework for understanding this ancient mystery.

Article Details

Issue

Vol. 1 No. 3 (2025)

Section

Opinion and Commentary
Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Articles published in Longevity Horizon fall under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND 4.0). This means authors retain their copyright while granting the journal the right to be the first publisher. Readers are permitted to share and distribute the work as long as proper credit is given. However, the content may not be altered, modified, or used for commercial purposes.

Author Biography

Jaba Tkemaladze, Longevity Clinic

A physician-scientist specializing in the biology of ageing and longevity. His research focuses on the potential of stem cell therapies for age-related diseases and healthspan extension.

Current Roles:

  • President, Longevity Alliance Georgia.
  • Head of Department, Longevity Clinic, Inc., Georgia.

Research Focus:
His primary research involves exploring methodologies for cellular rejuvenation, specifically the potential application of induced pluripotent stem (iPS) cell technology to regenerate aged tissues. His theoretical work includes the development of the Centriolar Theory of Differentiation and the Centriolar Theory of Organismal Ageing, which propose a role for the centriole in cellular ageing and development.

Background:
Dr. Tkemaladze trained in medicine at Tbilisi State Medical University and pursued further research in the laboratory of the Institute of Morphology at the Psychiatry Research Institute. His work employs a combined approach of experimental and computational methods to study the ageing process and develop interventions for age-related diseases.

Service and Recognition:
He has served on scientific advisory boards, including for the Georgian Ministry of Defense and the Longevity Alliance. He is the author of over 100 scientific publications and has been an invited speaker at numerous national and international conferences.

How to Cite

Tkemaladze, J. (2025). Theory of Lifespan Decline. Longevity Horizon, 1(3). DOI:https://doi.org/10.5281/zenodo.17142909
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